产品货号：
JN1806
中文名称：
重组小鼠Legumain(天冬酰胺肽链内切酶)(天冬氨酸内肽酶)
英文名称：
Recombinant Mouse Legumain/Asparaginyl Endopeptidase
产品规格：
10μg|50μg|500μg|1mg
发货周期：
1～3天
产品价格：
询价
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Val18-Tyr435在C端含有His标签。
Legumain质量控制：＞95%(还原性SDS-PAGE)
Legumain制剂：液体
Legumain保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。
关于Legumain：
Mouse Legumain,also known as LGMN, is a cysteine protease belonging to peptidase family C13 and is expressed in kidney and placenta abundantly. LGMN has a strict specificity for hydrolysis of asparaginyl bonds. It can also cleave aspartyl bonds slowly, especially under acidic conditions. The mammalian legumain is involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. It plays a role in the regulation of cell proliferation via its role in EGFR degradation. Legumain deficiency causes the accumulation of pro-Cathepsins B, H and L, another group of lysosomal cysteine proteases. Overexpression of Legumain in tumors is significant for invasion/metastasis. Mammalian legumain is inhibited by iodoacetamide and maleimides. Legumain activation appears to be autocatalytic and can be triggered by acidic pH.
相关搜索：重组小鼠Legumain(天冬酰胺肽链内切酶)(天冬氨酸内肽酶)
Legumain质量控制：＞95%(还原性SDS-PAGE)
Legumain制剂：液体
Legumain保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。
关于Legumain：
Mouse Legumain,also known as LGMN, is a cysteine protease belonging to peptidase family C13 and is expressed in kidney and placenta abundantly. LGMN has a strict specificity for hydrolysis of asparaginyl bonds. It can also cleave aspartyl bonds slowly, especially under acidic conditions. The mammalian legumain is involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. It plays a role in the regulation of cell proliferation via its role in EGFR degradation. Legumain deficiency causes the accumulation of pro-Cathepsins B, H and L, another group of lysosomal cysteine proteases. Overexpression of Legumain in tumors is significant for invasion/metastasis. Mammalian legumain is inhibited by iodoacetamide and maleimides. Legumain activation appears to be autocatalytic and can be triggered by acidic pH.
相关搜索：重组小鼠Legumain(天冬酰胺肽链内切酶)(天冬氨酸内肽酶)