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产品目录

重组小鼠ICOS(AILIM)(CD278)图片
产品货号:
JN1647
中文名称:
重组小鼠ICOS(AILIM)(CD278)
英文名称:
Recombinant Mouse Inducible T-cell Costimulator
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Glu21-Leu142在C端含有His标签。

ICOS/AILIM/CD278质量控制:>95%(还原性SDS-PAGE)

ICOS/AILIM/CD278制剂:冻干品

ICOS/AILIM/CD278保存
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

ICOS/AILIM/CD278复溶
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。

关于ICOS/AILIM/CD278
Inducible Costimulator(ICOS) is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA4 and PD1. ICOS shares approximately 39% amino acid similarity with CD 28 and CTLA4. Mouse and human ICOS share approximately 72% amino acid identity. ICOS is expressed on most CD45RO+ cells. ICOS expression is up-regulated within approximately 24-48 hours of activation on Th primed cells. B7-H2, a member of the B7 family of costimulatory ligands, has been identified as the ICOS ligand. The B7-H2/ ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation. In addition, ICOS is more potent in the induction of IL-10 production, acytokine important for suppressive function of T regulatory cells.
相关搜索:重组小鼠ICOS(AILIM)(CD278)Recombinant Mouse Inducible T-cell Costimulator
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