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产品目录

重组小鼠ST2(IL-1R4)图片
产品货号:
JN1447
中文名称:
重组小鼠ST2(IL-1R4)
英文名称:
Recombinant Mouse Interleukin-1 receptor-like 1
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ser27-Ala337在C端含有His标签。

ST2/IL-1 R4 质量控制:>95%(还原性SDS-PAGE)

ST2/IL-1 R4 制剂:冻干品

ST2/IL-1 R4 保存
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

ST2/IL-1 R4 复溶
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。

关于ST2/IL-1 R4
ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes. This receptor is very similar to the IL-1 receptor type I and the IL-18 receptor α chain in that ST2 also has three extracellular Ig domains and an intracellular Toll domain. ST2 binds IL-33, enhances inflammatory cytokines by activating nuclear factor-κB (NF-κB) and mitogen activated protein (MAP) kinases. ST2 exists as either a membrane bound form (ST2L) or as a soluble form (sST2). ST2L acts as a transmembrane signalling receptor for IL-33 by mediating the effect of IL-33 on the inflammatory process, while sST2 can suppress IL-33 activity.

相关搜索:重组小鼠ST2(IL-1R4)Recombinant Mouse Interleukin-1 receptor-like 1
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