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产品目录

重组小鼠DAN图片
产品货号:
JN1427
中文名称:
重组小鼠DAN
英文名称:
Recombinant Mouse Differential Screening-selected Gene Aberrant in Neuroblastoma
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ala17-Asp178在C端含有His标签。

DAN质量控制:>95%(还原性SDS-PAGE)

DAN制剂:冻干品

DAN保存
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

DAN复溶
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。

关于DAN
Differential screening-selected gene aberrative in neuroblastoma (DAN) is a member of the DAN family of secreted glycoproteins. DAN family antagonists are characterized by a DAN domain that contains a cystine knot motif which is essential for binding to BMP ligands. Members of this family include DAN, gremlin, protein related to DAN and cerberus (PRDC), cerberus, sclerostin (SOST) and uterine sensitization-associated gene 1 protein, and control diverse processes in growth, development and the cell cycle. It has also been reported that DAN family plays crucial role in early mouse embryo development by inhibiting the action of bone morphogenic proteins and modulating the action of transforming growth factor-β superfamily members. DAN is synthesized by small-to intermediate-sized DRG neurons and transported to the sensory nerve terminals in the skin or to the sensory nerve terminals in the dorsal horn. It has been reported that DAN is ubiquitously expressed in adult rat and human tissues. Morphological studies have revealed that, in adult rat, DAN mRNA is expressed ubiquitously in lung and brain, but not in liver.
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