产品货号：
JN1262
中文名称：
重组人HSD17B10(17β-羟基类固醇脱氢酶10)
英文名称：
Recombinant Human 17-beta-hydroxysteroid dehydrogenase 10
产品规格：
10μg|50μg|500μg|1mg
发货周期：
已停产
产品价格：
已停产
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Met1-Pro261在C端含有His标签。
HSD17B10质量控制：＞95%(还原性SDS-PAGE)
HSD17B10制剂：液体
HSD17B10保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。
关于HSD17B10：
3-hydroxyacyl-CoA dehydrogenase type-2(HSD17B10) belongs to the short-chain dehydrogenases/reductases (SDR) family. HSD17B10 is ubiquitously expressed in normal tissues but is overexpressed in neurons affected in AD. It functions in mitochondrial tRNA maturation. It catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. It also catalyzes the third step in the beta-oxidation of fatty acids and carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. The protein exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, HSD17B10 may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
相关搜索：重组人HSD17B10(17β-羟基类固醇脱氢酶10)
HSD17B10质量控制：＞95%(还原性SDS-PAGE)
HSD17B10制剂：液体
HSD17B10保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。
关于HSD17B10：
3-hydroxyacyl-CoA dehydrogenase type-2(HSD17B10) belongs to the short-chain dehydrogenases/reductases (SDR) family. HSD17B10 is ubiquitously expressed in normal tissues but is overexpressed in neurons affected in AD. It functions in mitochondrial tRNA maturation. It catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. It also catalyzes the third step in the beta-oxidation of fatty acids and carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. The protein exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, HSD17B10 may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
相关搜索：重组人HSD17B10(17β-羟基类固醇脱氢酶10)