产品货号：
JN0950
中文名称：
重组人蛋白精氨酸甲基转移酶1(PRMT1)
英文名称：
Recombinant Human Protein Arginine N-Methyltransferase 1
产品规格：
10μg|50μg|500μg|1mg
发货周期：
1～3天
产品价格：
询价
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Arg343在N端含有His标签。
PRMT1质量控制：＞95%(还原性SDS-PAGE)
PRMT1制剂：液体
PRMT1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。
关于PRMT1：
Protein Arginine N-Methyltransferase 1 (PRMT1) is a cytoplasmic protein that belongs to the protein arginine N-methyltransferase family. PRMT1 is a arginine methyltransferase that functions as a histone methyltransferase for H4. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes. PRMT1 methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. PRMT1 is responsible for the majority of cellular arginine methylation activity. Together with dimethylated PIAS1, it represses STAT1 transcriptional activity in the late phase of interferon gamma (IFN-gamma) signaling. It may be involved in the regulation of TAF15 transcriptional activity, act as an activator of estrogen receptor (ER)-mediated transactivation, play a key role in neurite outgrowth and serve as a negative regulator of megakaryocytic differentiation, by modulating p38 MAPK pathway.
相关搜索：重组人蛋白精氨酸甲基转移酶1(PRMT1)
PRMT1质量控制：＞95%(还原性SDS-PAGE)
PRMT1制剂：液体
PRMT1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。
关于PRMT1：
Protein Arginine N-Methyltransferase 1 (PRMT1) is a cytoplasmic protein that belongs to the protein arginine N-methyltransferase family. PRMT1 is a arginine methyltransferase that functions as a histone methyltransferase for H4. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes. PRMT1 methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. PRMT1 is responsible for the majority of cellular arginine methylation activity. Together with dimethylated PIAS1, it represses STAT1 transcriptional activity in the late phase of interferon gamma (IFN-gamma) signaling. It may be involved in the regulation of TAF15 transcriptional activity, act as an activator of estrogen receptor (ER)-mediated transactivation, play a key role in neurite outgrowth and serve as a negative regulator of megakaryocytic differentiation, by modulating p38 MAPK pathway.
相关搜索：重组人蛋白精氨酸甲基转移酶1(PRMT1)