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产品目录

重组人SIAE(唾液酸O-乙酰酯酶)图片
产品货号:
JN0808
中文名称:
重组人SIAE(唾液酸O-乙酰酯酶)
英文名称:
Recombinant Human Sialate O-Acetylesterase
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ile24-Lys523在C端含有His标签。

SIAE质量控制:>95%(还原性SDS-PAGE)

SIAE制剂:液体

SIAE保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。

关于SIAE
Sialate O-Acetylesterase (SIAE) belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. SIAE is widely expressed with high expression levels in the testis, prostate, and colon. SIAE catalyzes N-acetyl-O-acetylneuraminate and H2O to N-acetylneuraminate and acetate. SIAE removes O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. SIAE down-regulates B lymphocyte antigen receptor signaling (involving CD22), and is required for immunological tolerance. Loss of function mutations in SIAE are much more frequently found in humans with autoimmune diseases especially rheumatoid arthritis and type 1 diabetes.
相关搜索:重组人SIAE(唾液酸O-乙酰酯酶)Recombinant Human Sialate O-Acetylesterase
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