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产品目录

重组人促肾上腺皮质激素释放因子结合蛋白(CRHBP)(CRFBP)图片
产品货号:
JN0641
中文名称:
重组人促肾上腺皮质激素释放因子结合蛋白(CRHBP)(CRFBP)
英文名称:
Recombinant Human Corticotropin-Releasing Factor-Binding Protein
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Tyr25-Leu322在C端含有His标签。

CRHBP质量控制:>95%(还原性SDS-PAGE)

CRHBP制剂:冻干品

CRHBP保存
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

CRHBP复溶
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。

关于CRHBP
Corticotropin-Releasing Factor-Binding Protein (CRHBP) is a 37 kDa secreted glycoprotein that binds both CRH and urocortin in a 42 kDa extracellular complex. The molecule is approximately 300 amino acids in length and demonstrates five intrachain disulfide bonds. Difference between CRHBP from different species exist, human CRHBP is found in plasma while rodent and sheep CRHBP is limited to neuroendocrine tissues. CRHBP may inactivate CRH and may prevent inappropriate pituitary-adrenal stimulation in pregnancy. CRHBP is presumed to either sequester CRH, rendering it unavailable to cells or transport it to target tissues. Although CRF-BP concentration in the human peripheral circulation is normally low, it increases throughout pregnancy and fall back rapidly after parturition.
相关搜索:重组人促肾上腺皮质激素释放因子结合蛋白(CRHBP)(CRFBP)
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