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产品目录

重组人OX40(TNFRSF4)(CD134)(N端Fc标签)图片
产品货号:
JN0489
中文名称:
重组人OX40(TNFRSF4)(CD134)(N端Fc标签)
英文名称:
Recombinant Human OX40L receptor
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Leu29-Ala216在N端带有Fc标签。

OX40/TNFRSF4/CD134质量控制:>95%(还原性SDS-PAGE)

OX40/TNFRSF4/CD134制剂:冻干品

OX40/TNFRSF4/CD134保存
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

OX40/TNFRSF4/CD134复溶
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。

关于OX40/TNFRSF4/CD134
OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases.
相关搜索:重组人OX40(TNFRSF4)(CD134)(N端Fc标签)Recombinant Human OX40L receptor
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