产品目录

分子量：Approximately 11.5kDa,a single non-glycosylated polypeptide chain containing 98 amino acids.
储存条件：冷冻（-20℃）

概述

CXCL17 also named dendritic cell and monocyte chemokine-like protein(DMC)and VEGF co-regulated chemokine 1(VCC-1),is a small cytokine belonging to the CXC chemokine family.It is constitutively expressed in the lung and can be detected in trachea,stomach and skeletal muscle.CXCL17 attracts dendritic cells and monocytes and is regulated in tumors.It may be a housekeeping chemokine regulating recruitment of nonactivated blood monocytes and immature dendritic cells into tissues and may play a role in the innate defense against infections.Mature human CXCL17 shares 73%,71%and 64%amino acid sequence identity with bovine,mouse and rat CXCL17,respectively.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞96%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by its ability to induce VEGF expression using murine endothelial cells is less than 5.0μg/ml,corresponding to a specific activity of>200 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4,with 3%Trehalose.
内毒素	Less than 0.1 EU/μg of rHuVCC-1/CXCL17 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	SSLNPGVARG HRDRGQASRR WLQEGGQECE CKDWFLRAPR RKFMTVSGLP KKQCPCDHFK GNVKKTRHQR HHRKPNKHSR ACQQFLKQCQ LRSFALPL

相关搜索：重组人VCC-1/CXCL17，VCC-1/CXCL17, Human