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产品目录

重组Hirudin图片
产品货号:
GS4883
中文名称:
重组Hirudin
英文名称:
Recombinant Hirudin
产品规格:
2μg
发货周期:
1~3天
产品价格:
询价
分子量:Approximately 6.7kDa,a single non-glycosylated polypeptide chain containing 63 amino acid residues.
储存条件:冷冻(-20℃)

概述

Hirudin is the most potent natural thrombin-specific protease inhibitor,and is originally derived in the salivary glands of the medicinal leech.Unlike heparin,hirudin act directly on thrombin,rather than through other clotting factors.They have a high binding affinity and specificity for thrombin.Therefore,hirudin prevents or dissolves the formation of clots and thrombi,and has therapeutic value in blood coagulation disorders,in the treatment of skin hematomas and of superficial varicose veins,either as an injectable or a topical application cream.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观Sterile Filtered White lyophilized(freeze-dried)powder.
纯度>96%by SDS-PAGE and HPLC analyses.
来源Pichia Pastoris
生物活性The biological activity is determined by chromogenic assay,1 unit is defined as the amount of Hirudin that neutralizes 1 unit of the WHO preparation 89/588 of thrombin.The specific activity is no less than 14,000 ATU/mg protein.
成分Lyophilized from a 0.2μmfiltered solution of 20mMPBS,pH 7.0,containing 2%mannitol.
内毒素Less than 1 EU/μg of rHirudin as determined by LAL method.
复溶We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列VVYTDCTESG QNLCLCEGSN VCGQGNKCIL GSDGEKNQCV TGEGTPGPQS HNDGDFEEPE EYL

相关搜索:重组HirudinHirudin, RecombinantRecombinant Hirudin
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