产品货号:
GS4851
中文名称:
重组人GRO-γ/CXCL3
英文名称:
Recombinant Human Growth Regulated Protein-gamma/CXCL3
产品规格:
2μg
发货周期:
1~3天
产品价格:
询价
分子量:Approximately 7.9kDa,a single non-glycosylated polypeptide chain containing 73 amino acids.
储存条件:冷冻(-20℃)
概述
CXCL3,also named GRO-γ,is belonging to the CXC chemokine family and encoded by the gene CXCL3.CXCL3/GRO-γ shares 86%amino acid sequence with CXCL1/GRO-α.All three human GROs(GRO-α,GRO-β,GRO-γ)are members of the intercrine alpha(chemokine C-X-C)subfamily of chemokines.This chemokine is secreted by monocytes and macrophages.The functional receptor for CXCL3 has been identified as CXCR2.Similar to other GRO proteins,CXCL3 is potent neutrophil attractants and activators.CXCL3 plays a role in inflammation and exert its effects on endothelial cells in an autocrine fashion.All three GROs can bind with high affinity to the IL-8 receptor type B.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索:重组人GRO-γ/CXCL3,GRO-γ/CXCL3, Human
储存条件:冷冻(-20℃)
概述
CXCL3,also named GRO-γ,is belonging to the CXC chemokine family and encoded by the gene CXCL3.CXCL3/GRO-γ shares 86%amino acid sequence with CXCL1/GRO-α.All three human GROs(GRO-α,GRO-β,GRO-γ)are members of the intercrine alpha(chemokine C-X-C)subfamily of chemokines.This chemokine is secreted by monocytes and macrophages.The functional receptor for CXCL3 has been identified as CXCR2.Similar to other GRO proteins,CXCL3 is potent neutrophil attractants and activators.CXCL3 plays a role in inflammation and exert its effects on endothelial cells in an autocrine fashion.All three GROs can bind with high affinity to the IL-8 receptor type B.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
纯度 | >97%by SDS-PAGE and HPLC analyses. |
来源 | Escherichia coli. |
生物活性 | Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is in a concentration range of 10-100ng/ml. |
成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,50 mM NaCl. |
内毒素 | Less than 1 EU/μg of rHuGRO-γ/CXCL3 as determined by LAL method. |
复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
氨基酸序列 | ASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN |
相关搜索:重组人GRO-γ/CXCL3,GRO-γ/CXCL3, Human