重组小鼠Bcl-xL

产品货号：

GS4757

中文名称：

重组小鼠Bcl-xL

英文名称：

Recombinant Murine B-cell lymphoma-extra large

产品规格：

2μg

发货周期：

1～3天

产品价格：

询价

分子量：Approximately 23.7kDa,a single non-glycosylated polypeptide chain containing 211 amino acids.
储存条件：冷冻（-20℃）

概述

Bcl-xL is a transmembrane protein located in the mitochondrial membranes of cells that are long-lived and postmitotic,such as adult brain cells.It plays a role in the signal transduction pathway of the FAS-Ligand.Bcl-xL is an anti-apoptotic protein which is a member of the Bcl-2 family which are able to form heterodimers,and this is an significant event in the regulation of apoptosis.It is involved in the survival of cancer cells.Bcl-xL is the leading monitor of apoptosis/active cell suicide.It has cell death repressor activity and therefore acts as a survival protein.The murine Bcl-xL shares 97%and 99%a.a.sequence identity with human and rat Bcl-xL,respectively.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Test in Process.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 2×PBS,pH 7.4,5%Trehalose.
内毒素	Less than 0.1 EU/μg of rMuBcl-xL as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	SQSNRELVVD FLSYKLSQKG YSWSQFSDVE ENRTEAPEET EAERETPSAI NGNPSWHLAD SPAVNGATGH SSSLDAREVI PMAAVKQALR EAGDEFELRY RRAFSDLTSQ LHITPGTAYQ SFEQVVNELF RDGVNWGRIV AFFSFGGALC VESVDKEMQV LVSRIASWMA TYLNDHLEPW IQENGGWDTF VDLYGNNAAA ESRKGQERFN R

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