产品货号：
GS4731
中文名称：
重组大鼠MIP-1α/CCL3
英文名称：
Recombinant Rat Macrophage Inflammatory Protein-1 alpha/CCL3
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 7.9kDa,a single non-glycosylated polypeptide chain containing 69 amino acids.
储存条件：冷冻（-20℃）
概述
Chemokine(C-C motif)ligand 3 encoded by the CCL3 gene,also known as macrophage inflammatory protein-1α(MIP-1α)is a CC chemokine with specificity for CCR5 receptors and it is a major HIV-suppressive factor produced by CD8+ T cells.In addition,it is a chemoattractant for natural killer cells,monocytes and a variety of other immune cells.Recombinant CCL3 induces a dose-dependent inhibition of different strains of HIV-1,HIV-2,and simian immunodeficiency virus(SIV).Furthermore,recombinant rat CCL3 contains 69 amino acids and it shares 72%and 91%a.a.sequence identity with human and murine CCL3.Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组大鼠MIP-1α/CCL3，MIP-1α/CCL3, Rat
储存条件：冷冻（-20℃）
概述
Chemokine(C-C motif)ligand 3 encoded by the CCL3 gene,also known as macrophage inflammatory protein-1α(MIP-1α)is a CC chemokine with specificity for CCR5 receptors and it is a major HIV-suppressive factor produced by CD8+ T cells.In addition,it is a chemoattractant for natural killer cells,monocytes and a variety of other immune cells.Recombinant CCL3 induces a dose-dependent inhibition of different strains of HIV-1,HIV-2,and simian immunodeficiency virus(SIV).Furthermore,recombinant rat CCL3 contains 69 amino acids and it shares 72%and 91%a.a.sequence identity with human and murine CCL3.Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞98%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The biological activity determined by a chemoattract bioassay using human blood monocytes is in a concentration range of 10-100ng/ml. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 30%Acetonitrile and 0.1%TFA. |
| 内毒素 | Less than 0.1 EU/μg of rRtMIP-1α/CCL3 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | APYGADTPTA CCFSYGRQIP RKFIADYFET SSLCSQPGVI FLTKRNRQIC ADPKETWVQE YITELELNA |
相关搜索：重组大鼠MIP-1α/CCL3，MIP-1α/CCL3, Rat