产品目录

分子量：Approximately 8.7kDa,a single non-glycosylated polypeptide chain containing 76 amino acids and comprises only the chemokine domain of Murine Fractalkine.
储存条件：冷冻（-20℃）

概述

CX3CL1 recently identified through bioinformatics is the only known member of the CX3C chemokine family and it is also commonly known under the names fractalkine(in humans)and neurotactin(in mice).Unlike other known chemokines,CX3CL1 is a type 1 membrane protein containing a chemokine domain tethered on a long mucinlike talk.The soluble form of CX3CL1 is chemotactic for T-cells and monocytes,but not for neutrophils.In addition,it may play a role in regulating leukocyte adhesion and migration processes at the endothelium.Recombinant Murine CX3CL1 contains 76 amino acids and it shares approximately 85%and 77%amino acid sequence homology with the rat and human protein.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using human peripheral blood lymphocytes(PBL)is less than 0.5μg/ml,corresponding to a specific activity of>2000 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
内毒素	Less than 0.1 EU/μg of rMuFractalkine/CX3CL1 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	QHLGMTKCEI MCGKMTSRIP VALLIRYQLN QESCGKRAIV LETTQHRRFC ADPKEKWVQD AMKHLDHQAA ALTKNG

相关搜索：重组小鼠Fractalkine/CX3CL1，Fractalkine/CX3CL1, Murine，Recombinant Murine Fractalkine/CX3CL1