产品货号：
GS4704
中文名称：
重组大鼠IL-2
英文名称：
Recombinant Rat Interleukin-2
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 15.5kDa,a single non-glycosylated polypeptide chain containing 135 amino acids.
储存条件：冷冻（-20℃）
概述
IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation.It is expressed by CD4+ and CD8+ T cells,γδ T cells,B cells,dendritic cells,and eosinophils.IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response.The receptor for IL-2 consists of three subunits(55 kDa IL2Rα,75 kDa IL2Rβ,64 kDa common gamma chain γc/IL2Rγ)that are present on the cell surface in varying preformed complexes.Recombinant rat IL-2 is a 15.3 kDa protein containing 134 amino acid residues and it shares about 82%,66%,66%,60%and 54%amino acid sequence identity with mouse,human,rhesus macaque,pig and equus caballus IL-2,respectively.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组大鼠IL-2，IL-2, Rat，Recombinant Rat Interleukin-2
储存条件：冷冻（-20℃）
概述
IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation.It is expressed by CD4+ and CD8+ T cells,γδ T cells,B cells,dendritic cells,and eosinophils.IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response.The receptor for IL-2 consists of three subunits(55 kDa IL2Rα,75 kDa IL2Rβ,64 kDa common gamma chain γc/IL2Rγ)that are present on the cell surface in varying preformed complexes.Recombinant rat IL-2 is a 15.3 kDa protein containing 134 amino acid residues and it shares about 82%,66%,66%,60%and 54%amino acid sequence identity with mouse,human,rhesus macaque,pig and equus caballus IL-2,respectively.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.2ng/ml,corresponding to a specific activity of>5.0×106 IU/mg. |
| 成分 | A 0.2μmfiltered concentrated sterile solution in 10mMsodium citrate,pH 4.0. |
| 内毒素 | Less than 1 EU/μg of rRtIL-2 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | APTSSPAKET QQHLEQLLLD LQVLLRGIDN YKNLKLPMML TFKFYLPKQA TELKHLQCLE NELGALQRVL DLTQSKSFHL EDAGNFISNI RVTVVKLKGS ENKFECQFDD EPATVVEFLR RWIAICQSII STMTQ |
相关搜索：重组大鼠IL-2，IL-2, Rat，Recombinant Rat Interleukin-2