产品货号：
GS4683
中文名称：
重组小鼠IL-5
英文名称：
Recombinant Murine Interleukin-5
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 26.2kDa,a disulfide-linked homodimeric protein containing two 113 amino acids.
储存条件：冷冻（-20℃）
概述
IL-5,also named B-cell differentiation factor I,eosinophil differentiation factor and TRF,is belonging to the cytokine family and the IL-5 gene is in close proximity to the genes encoding IL-3,IL-4,and granulocyte-macrophage colony-stimulating factor(GM-CSF),which are often co-expressed in TH2 cells.Through binding to the IL-5 receptor,IL-5 stimulates B cell growth and increases immunroglobulin secretion.It is also a key mediator in eosinophil activation.Interleukin-5 has long been associated with the cause of several allergic diseases including allergic rhinitis and asthma.Murine IL-5 is a 113-amino acid(115 in human,113 in rat)-long TH2 cytokine that is part of the hematopoietic family.Unlike other members of this cytokine family(namely IL-3 and GM-CSF),this glycoprotein in its active form is a homodimer.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组小鼠IL-5，IL-5, Murine，Recombinant Murine Interleukin-5
储存条件：冷冻（-20℃）
概述
IL-5,also named B-cell differentiation factor I,eosinophil differentiation factor and TRF,is belonging to the cytokine family and the IL-5 gene is in close proximity to the genes encoding IL-3,IL-4,and granulocyte-macrophage colony-stimulating factor(GM-CSF),which are often co-expressed in TH2 cells.Through binding to the IL-5 receptor,IL-5 stimulates B cell growth and increases immunroglobulin secretion.It is also a key mediator in eosinophil activation.Interleukin-5 has long been associated with the cause of several allergic diseases including allergic rhinitis and asthma.Murine IL-5 is a 113-amino acid(115 in human,113 in rat)-long TH2 cytokine that is part of the hematopoietic family.Unlike other members of this cytokine family(namely IL-3 and GM-CSF),this glycoprotein in its active form is a homodimer.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞98%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 2ng/ml,corresponding to a specific activity of>5.0×105 IU/mg. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 20mMTris,pH 9.0,150 mM NaCl. |
| 内毒素 | Less than 0.1 EU/μg of rMuIL-5 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR TRQFLDYLQE FLGVMSTEWA MEG |
相关搜索：重组小鼠IL-5，IL-5, Murine，Recombinant Murine Interleukin-5