重组Exendin-4

产品货号：

GS4647

中文名称：

重组Exendin-4

英文名称：

Recombinant Exendin-4

产品规格：

20μg

发货周期：

1～3天

产品价格：

询价

分子量：Approximately 4.2kDa,a single non-glycosylated polypeptide chain containing 39 amino acids.
储存条件：冷冻（-20℃）

概述

Exendin-4 is a novel 39-amino acid peptide isolated from the venom of the Gila monster Heloderma suspectum.It shares 53%sequence homology with GLP-17-36amide and interacts with the same membrane receptor.Exendin-4 enhances glucose-dependent insulin secretion,suppresses inappropriately elevated glucagon secretion,and slows gastric emptying in vivo.It also promotes?-cell proliferation and neogenesis in vitro and in animal models.Recombinant Exendin-4 is E.coli expression of a synthetic DNA sequence encoding the 39 amino acid of Exendin-4.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞96%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	1.Regulates Glucose levels rapidly;2.Reduces Insulin resistance;3.Reduces Glucagon;4.Reduces HbA1c;5.Stimulates beta cell growth which stimulates insulin production.
成分	Lyophilized from a 0.2μmfiltered solution in PBS,pH 7.4.
内毒素	Less than 10 EU/mg of rExendin-4 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	HGEGTFTSDL SKQMEEEAVR LFIEWLKNGG PSSGAPPPS

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