产品货号：
GS4597
中文名称：
重组小鼠PF-4/CXCL4
英文名称：
Recombinant Murine Platelet Factor-4/CXCL4
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 8.2kDa,a single non-glycosylated polypeptide chain containing 76 amino acids.
储存条件：冷冻（-20℃）
概述
CXCL4(PF4)is a small cytokine belonging to the CXC chemokine family and it is also known as chemokine(C-X-C motif)ligand 4(CXCL4).This chemokine is released from alpha-granules of activated platelets during platelet aggregation and neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule.CXCL4 interacts with a splice variant of the chemokine receptor CXCR3.Recombinant mouse CXCL4 contains 76 amino acids which is a single non-glycosylated polypeptide chain.Specifically,Human and mouse CXCL4 share about a 60%identity.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组小鼠PF-4/CXCL4，PF-4/CXCL4, Murine，Recombinant Murine Platelet Factor-4/CXCL4
储存条件：冷冻（-20℃）
概述
CXCL4(PF4)is a small cytokine belonging to the CXC chemokine family and it is also known as chemokine(C-X-C motif)ligand 4(CXCL4).This chemokine is released from alpha-granules of activated platelets during platelet aggregation and neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule.CXCL4 interacts with a splice variant of the chemokine receptor CXCR3.Recombinant mouse CXCL4 contains 76 amino acids which is a single non-glycosylated polypeptide chain.Specifically,Human and mouse CXCL4 share about a 60%identity.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration of 10-100ng/ml. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,1.5MNaCl,pH 7.4. |
| 内毒素 | Less than 1 EU/μg of rMuPF-4/CXCL4 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | VTSAGPEESD GDLSCVCVKT ISSGIHLKHI TSLEVIKAGR HCAVPQLIAT LKNGRKICLD RQAPLYKKVI KKILES |
相关搜索：重组小鼠PF-4/CXCL4，PF-4/CXCL4, Murine，Recombinant Murine Platelet Factor-4/CXCL4