产品货号：
GS4506
中文名称：
重组小鼠KC/CXCL1
英文名称：
Recombinant Murine KC/CXCL1
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
General Description:
Murine CXCL1,also known as KC,is belonging to the CXC chemokine family.It is encoded by the GRO gene now designated CXCL1.The gene for CXCL1 was initially discovered in mouse fibroblasts by plateletderived growth factor.KC is member of the intercrine alpha (chemokine C-X-C) subfamily of chemokines.It is secreted by human melanoma cells,and also expressed by macrophages,neutrophils and epithelial cells.The functional receptor for CXCL1 has been identified as CXCR2.CXCL1 has chemotactic activity for neutrophils,and plays a role in inflammation and wound healing.Amino acid sequence of murine CXCL1 is approximately 60% identical to the human CXCL1.KC was found to be involved in monocyte arrest on atherosclerotic endothelium and may also play a pathophysiological role in Alzheimer's disease.
Storage:
This lyophilized preparation is stable at 2～8℃,but should be kept at -20℃ for long term storage,preferably desiccated.Upon reconstitution,the preparation is stable for up to one week at 2～8℃.For maximal stability,apportion the reconstituted preparation into working aliquots and store at -20℃ to -70℃.Avoid repeated freeze/thaw cycles.
Usage:
This material is offered by bjbalb Biotech for research,laboratory or further evaluation purposes.
NOT FOR HUMAN USE.
Molecular Weight:
Approximately 7.8kDa,a single non-glycosylated polypeptide chain containing 72 amino acid residues.
Purity:
> 97% by SDS-PAGE and HPLC analyses.
Source:
Escherichia coli.
Biological Activity:
Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration range of 10～100ng/mL.
Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:
Lyophilized from a 0.2μm filtered concentrated solution in PBS,pH7.4.
Endotoxin:
Less than 1 EU/μg of rMuKC/CXCL1 as determined by LAL method.
Reconstitution:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1～1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃.Further dilutions should be made in appropriate buffered solutions.
AA Sequence:
APIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREA CLDPEAPLVQ KIVQKMLKGV PK
Murine CXCL1,also known as KC,is belonging to the CXC chemokine family.It is encoded by the GRO gene now designated CXCL1.The gene for CXCL1 was initially discovered in mouse fibroblasts by plateletderived growth factor.KC is member of the intercrine alpha (chemokine C-X-C) subfamily of chemokines.It is secreted by human melanoma cells,and also expressed by macrophages,neutrophils and epithelial cells.The functional receptor for CXCL1 has been identified as CXCR2.CXCL1 has chemotactic activity for neutrophils,and plays a role in inflammation and wound healing.Amino acid sequence of murine CXCL1 is approximately 60% identical to the human CXCL1.KC was found to be involved in monocyte arrest on atherosclerotic endothelium and may also play a pathophysiological role in Alzheimer's disease.
Storage:
This lyophilized preparation is stable at 2～8℃,but should be kept at -20℃ for long term storage,preferably desiccated.Upon reconstitution,the preparation is stable for up to one week at 2～8℃.For maximal stability,apportion the reconstituted preparation into working aliquots and store at -20℃ to -70℃.Avoid repeated freeze/thaw cycles.
Usage:
This material is offered by bjbalb Biotech for research,laboratory or further evaluation purposes.
NOT FOR HUMAN USE.
Molecular Weight:
Approximately 7.8kDa,a single non-glycosylated polypeptide chain containing 72 amino acid residues.
Purity:
> 97% by SDS-PAGE and HPLC analyses.
Source:
Escherichia coli.
Biological Activity:
Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration range of 10～100ng/mL.
Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:
Lyophilized from a 0.2μm filtered concentrated solution in PBS,pH7.4.
Endotoxin:
Less than 1 EU/μg of rMuKC/CXCL1 as determined by LAL method.
Reconstitution:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1～1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃.Further dilutions should be made in appropriate buffered solutions.
AA Sequence:
APIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREA CLDPEAPLVQ KIVQKMLKGV PK
相关搜索：重组小鼠KC/CXCL1，KC/CXCL1, Murine，Recombinant Murine KC/CXCL1