产品目录

分子量：Approximately 7.9kDa,a single non-glycosylated polypeptide chain containing 73 amino acids.
储存条件：冷冻（-20℃）

概述

CXCL2,also named GRO-β,is belonging to the CXC chemokine family.It is encoded by the gene CXCL2 in humans.CXCL2/GROβ shares 90%amino acid sequence with CXCL1/GRO-α.All three human GROs(GRO-α,GRO-β,GRO-γ)are members of the intercrine alpha(chemokine C-X-C)subfamily of chemokine.This chemokine is secreted by monocytes and macrophages.The functional receptor for CXCL2 has been identified as CXCR2.CXCL2 is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells.Similar to other GRO proteins,CXCL2 is potent neutrophil attractants and activators.In addition,it is also active toward basophils.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is in a concentration range of 10-100ng/ml.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,50 mM NaCl.
内毒素	Less than 1 EU/μg of rHuGRO-β/CXCL2 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	APLATELRCQ CLQTLQGIHL KNIQSVKVKS PGPHCAQTEV IATLKNGQKA CLNPASPMVK KIIEKMLKNG KSN

相关搜索：重组人GRO-β/CXCL2，GRO-β/CXCL2, Human