产品货号：
Z39530
中文名称：
PTP1B/PTPN1抗体
英文名称：
Anti-PTP1B/PTPN1 Antibody (Clone#OTI1B4)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PTP1B/PTPN1 Antibody (Clone#OTI1B4) |
| 指标别名 | PTP 1B;PTP1B;PTPN1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,rat |
| 应用范围 | WB,FCM |
| 基因名称 | PTPN1 |
| 克隆号 | OTI1B4 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2a |
| 免疫原 | Full length human recombinant protein of human PTPN1 (NP_002818) produced in HEK293T cell. |
| 实际分子量 | 49.8KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family,which was isolated and identified based on its enzymatic activity and amino acid sequence.PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues.Members of the PTP family share a highly conserved catalytic motif,which is essential for the catalytic activity.PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth,differentiation,mitotic cycle,and oncogenic transformation.This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase.This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase,as well as JAK2 and TYK2 kinases,which implicated the role of this PTP in cell growth control,and cell response to interferon stimulation.[provided by RefSeq] |
| Uniprot ID | P18031 |
| 基因名全称 | protein tyrosine phosphatase,non-receptor type 1 |
| 蛋白名全称 | Tyrosine-protein phosphatase non-receptor type 1 |
| 推荐稀释比 | Western blot (WB) 1:2000 Flow cytometry (FCM) 1:100 |
相关搜索：PTP1B/PTPN1抗体，PTP1B抗体，PTPN1单抗，Anti-PTP1B/PTPN1 Antibody (Clone#OTI1B4)