产品货号:
Z39454
中文名称:
SPRY2抗体
英文名称:
Anti-SPRY2 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-SPRY2 Antibody |
指标别名 | hSPRY2;Protein sprouty homolog 2;sprouty homolog 2 (Drosophila);Spry 2;SPRY2 |
克隆性 | Monoclonal |
检验物种 | human,rat |
应用范围 | WB |
基因名称 | SPRY2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human Sprouty 2 May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis. |
实际分子量 | 42KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Sprouty homolog 2 (Drosophila),also known as SPRY2,is a protein which in humans is encoded by the SPRY2 gene.It is mapped to 13q31.1.This gene encodes a protein belonging to the sprouty family.The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles.In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two.This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling.The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence,and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling.This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. |
Uniprot ID | O43597 |
推荐稀释比 | Western blot (WB) 1:500~2000 |
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