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所在位置:所有产品 > 抗体抗原 > 一抗 > UBE3A抗体
UBE3A抗体图片
产品货号:
Z39397
中文名称:
UBE3A抗体
英文名称:
Anti-UBE3A Antibody (Clone#8I3)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-UBE3A Antibody (Clone#8I3)
指标别名ANCR;AS;E6 AP;E6AP;E6AP ubiquitin protein ligase;EPVE6AP;HPVE6A;UBE3A;ubiquitin protein ligase E3A
克隆性Monoclonal
检验物种human,monkey
应用范围WB,FCM
基因名称UBE3A
克隆号8I3
抗体来源Mouse
抗体类型IgG2a
免疫原E.coli-derived human UBE3A recombinant protein (Position:M1-E860).
实际分子量100KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式protein G purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Ubiquitin-protein ligase E3A (UBE3A) also known as E6AP ubiquitin-protein ligase (E6AP) is an enzyme that in humans is encoded by the UBE3A gene.It is mapped to 15q11.2.This gene encodes an E3 ubiquitin-protein ligase,part of the ubiquitin protein degradation system.This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues.Maternally inherited deletion of this gene causes Angelman Syndrome,characterized by severe motor and intellectual retardation,ataxia,hypotonia,epilepsy,absence of speech,and characteristic facies.The protein also interacts with the E6 protein of human papillomavirus types 16 and 18,resulting in ubiquitination and proteolysis of tumor protein p53.Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini.Additional transcript variants have been described,but their full length nature has not been determined.
Uniprot IDQ05086
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC.
基因名全称ubiquitin protein ligase E3A
蛋白名全称Ubiquitin-protein ligase E3A
推荐稀释比
Western blot(WB) 1:500~2000
Flow cytometry (FCM) 1~3μg/1×106 cells

相关搜索:UBE3A抗体UBE3A单抗Anti-UBE3A Antibody (Clone#8I3)
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