产品货号：
Z39355
中文名称：
ZAP70抗体
英文名称：
Anti-ZAP70 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ZAP70 Antibody |
| 指标别名 | zeta chain of T cell receptor associated protein kinase 70;ADMIO2;IMD48;SRK;STCD;STD;TZK;ZAP-70;ZAP70 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,IP,FCM |
| 基因名称 | ZAP70 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human ZAP70 The Syk family protein tyrosine kinase Zap-70 is expressed in T and NK cells and plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement.Following TCR engagement,Zap-70 is rapidly phosphorylated on several tyrosine residues through autophosphorylation and transphosphorylation by the Src family tyrosine kinase Lck. |
| 实际分子量 | 70KD |
| 成分 | Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ZAP-70 (Zeta-chain-associated protein kinase 70) encodes an enzyme belonging to the protein tyrosine kinase family,and it plays a role in T-cell development and lymphocyte activation.This enzyme,which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation,functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases,Lck and Fyn.This enzyme is also essential for thymocyte development.Mutations in this gene cause selective T-cell defect,a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells.Two transcript variants that encode different isoforms have been found for this gene. |
| Uniprot ID | P43403 |
| 推荐稀释比 | Western blot (WB) 1:400～800 Immunohistochemistry in paraffin section (IHC) 1:20～100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 Immunocoprecipitation 1:20 Flow cytometry (FCM) 1:20 |
相关搜索：ZAP70抗体，ZAP70单抗，Anti-ZAP70 Antibody