产品货号:
Z39272
中文名称:
USP7抗体
英文名称:
Anti-USP7 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-USP7 Antibody |
指标别名 | Deubiquitinating enzyme 7;HAUSP;TEF1;Ubiquitin thioesterase 7;USP7 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | USP7 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human HAUSP/USP7 Hydrolase that deubiquitinates target proteins such as FOXO4,p53/TP53,MDM2,ERCC6,DNMT1,UHRF1,PTEN and DAXX (PubMed:11923872,PubMed:15053880,PubMed:16964248,PubMed:18716620,PubMed:25283148). |
实际分子量 | 128KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Ubiquitin-specific-processing protease 7 (USP7),also known as ubiquitin carboxyl-terminal hydrolase 7 or herpesvirus-associated ubiquitin-specific protease (HAUSP),is an enzyme that in humans is encoded by the USP7 gene.The protein encoded by this gene belongs to the peptidase C19 family,which includes ubiquitinyl hydrolases.This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling),and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27,involved in the respective process.Mutations in this gene have been implicated in a neurodevelopmental disorder. |
Uniprot ID | Q93009 |
推荐稀释比 | Western blot (WB) 1:500~2000 |
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