产品货号:
Z39245
中文名称:
ULK3抗体(C-term)
英文名称:
Anti-ULK3 Antibody(C-term)(Clone#1404CT148.89.25)
产品规格:
80μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ULK3 Antibody (C-term) (Clone#1404CT148.89.25) |
指标别名 | unc-51 like kinase 3;ULK3 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | ULK3 |
克隆号 | 1404CT148.89.25 |
抗体来源 | Mouse |
免疫原 | This ULK3 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 435-468 amino acids from the C-terminal region of human ULK3. |
计算分子量 | 53kDa |
成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
保存条件 | Maintain refrigerated at 2~8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
背景资料 | Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy.Acts as a negative regulator of SHH signaling in the absence of SHH ligand:interacts with SUFU,thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1,GLI2 and/or GLI3).Positively regulates SHH signaling in the presence of SHH:dissociates from SUFU,autophosphorylates and mediates phosphorylation of GLI2,activating it and promoting its nuclear translocation.Phosphorylates in vitro GLI2,as well as GLI1 and GLI3,although less efficiently.Also acts as a regulator of autophagy:following cellular senescence,able to induce autophagy. |
Uniprot ID | Q6PHR2 |
相关搜索:ULK3抗体(C-term),ULK3单抗,Anti-ULK3 Antibody(C-term)(Clone#1404CT148.89.25)