产品货号：
Z38926
中文名称：
SHARP1/BHLHE41抗体(N-term)
英文名称：
Anti-SHARP1/BHLHE41 Antibody(N-term)(Clone#2135CT82.1.84)
产品规格：
50μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SHARP1/BHLHE41 Antibody (N-term) (Clone#2135CT82.1.84) |
| 指标别名 | Class E basic helix-loop-helix protein 41;bHLHe41;Class B basic helix-loop-helix protein 3;bHLHb3;Differentially expressed in chondrocytes protein 2;hDEC2;Enhancer-of-split and hairy-related protein 1;SHARP-1;BHLHE41;BHLHB3;DEC2;SHARP1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | BHLHE41 |
| 克隆号 | 2135CT82.1.84 |
| 抗体来源 | Mouse |
| 免疫原 | This BHLH3 antibody is generated from a mouse immunized with a recombinant protein of human BHLH3. |
| 计算分子量 | 50kDa |
| 成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes.Acts as the negative limb of a novel autoregulatory feedback loop (DEC loop) which differs from the one formed by the PER and CRY transcriptional repressors (PER/CRY loop).Both these loops are interlocked as it represses the expression of PER1 and in turn is repressed by PER1/2 and CRY1/2.Represses the activity of the circadian transcriptional activator:CLOCK-ARNTL/BMAL1 heterodimer by competing for the binding to E-box elements (5'-CACGTG-3') found within the promoters of its target genes.Negatively regulates its own expression and the expression of DBP and BHLHE41/DEC2.Acts as a corepressor of RXR and the RXR-LXR heterodimers and represses the ligand-induced RXRA/B/G,NR1H3/LXRA,NR1H4 and VDR transactivation activity. |
| Uniprot ID | Q9C0J9 |
相关搜索：SHARP1/BHLHE41抗体(N-term)，SHARP1抗体，BHLHE41单抗