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产品目录

SHP2/PTPN11抗体图片
产品货号:
Z38916
中文名称:
SHP2/PTPN11抗体
英文名称:
Anti-SHP2/PTPN11 Antibody (Clone#2E6)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-SHP2/PTPN11 Antibody (Clone#2E6)
指标别名BPTP3;CFC;NS1;PTP 1D;PTP 2C;PTP2C;PTPN11;SH PTP2;SH PTP3;SHP 2;SHP2;SHPTP2
克隆性Monoclonal
检验物种human,mouse,rat
应用范围WB,IHC,ICC/IF,FCM
基因名称PTPN11
克隆号2E6
抗体来源Mouse
抗体类型IgG2b
免疫原A synthetic peptide corresponding to a sequence at the N-terminus of human SHP2 (69-99aa EKFATLAELVQYYMEHHGQLKEKNGDVIELK),identical to the related mouse and rat sequences.
实际分子量68KD
成分200μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式protein G purified.
浓度200μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料PTPN11 (Tyrosine-protein phosphatase non-receptor type 11),also known as protein-tyrosine phosphatase 1D (PTP-1D),protein-tyrosine phosphatase 2C (PTP-2C),TYROSINE PHOSPHATASE SHP2 (SHP2),BPTP3,SH-PTP2,SHP-2,SH-PTP3,is an enzyme that in humans is encoded by the PTPN11 gene.PTPN11 is a member of the protein tyrosine phosphatase (PTP) family.The open reading frame consists of 1,779 nucleotides potentially encoding a protein of 593 amino acids with a predicted molecular mass of 68kD.PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth,differentiation,mitotic cycle,and oncogenic transformation.This PTP contains two tandem Src homology-2 domains,which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates.This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions,such as mitogenic activation,metabolic control,transcription regulation,and cell migration.Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.
Uniprot IDQ06124
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。
推荐稀释比
Western blot(WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:50~400
Immunocytochemistry in fixed cells 1:50~400
Flow cytometry (FCM) 1~3μg/1×106 cells
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:SHP2/PTPN11抗体SHP2抗体PTPN11单抗Anti-SHP2/PTPN11 Antibody (Clone#2E6)
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