产品货号：
Z38849
中文名称：
VEGF/VEGFA抗体
英文名称：
Anti-VEGF/VEGFA Antibody (Clone#OTI4G3)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-VEGF/VEGFA Antibody (Clone#OTI4G3) |
| 指标别名 | L VEGFA;MVCD1;Vascular permeability factor;VEGF;VEGF A;VEGFA;VPF |
| 克隆性 | Monoclonal |
| 检验物种 | human,dog |
| 应用范围 | WB |
| 基因名称 | VEGFA |
| 克隆号 | OTI4G3 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | Human recombinant protein fragment corresponding to amino acids 27-233 of human VEGFA (NP_003367) produced in E.coli. |
| 实际分子量 | 23.8KD |
| 成分 | PBS (pH7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 0.46mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | Vascular endothelial growth factor A (VEGF-A) is a protein that in humans is encoded by the VEGFA gene.It is mapped to 17 C;17 22.79 cM.This gene is a member of the PDGF/VEGF growth factor family.It encodes a heparin-binding protein,which exists as a disulfide-linked homodimer.This growth factor induces proliferation and migration of vascular endothelial cells,and is essential for both physiological and pathological angiogenesis.Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation.This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression.Elevated levels of this protein are found in patients with POEMS syndrome,also known as Crow-Fukase syndrome.Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis.Alternatively spliced transcript variants encoding different isoforms have been described.There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms.A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism,and that this isoform is antiangiogenic.Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame,which is located within an internal ribosome entry site. |
| Uniprot ID | P15692 |
| 基因名全称 | vascular endothelial growth factor A |
| 蛋白名全称 | Vascular endothelial growth factor A |
| 推荐稀释比 | Western blot (WB) 1:2500～5000 |
相关搜索：VEGF/VEGFA抗体，VEGF抗体，VEGFA单抗，Anti-VEGF/VEGFA Antibody (Clone#OTI4G3)