产品货号：
Z38823
中文名称：
Hsp90 alpha/HSP90AA1抗体
英文名称：
Anti-Hsp90 alpha/HSP90AA1 Antibody (Clone#6B5)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Hsp90 alpha/HSP90AA1 Antibody (Clone#6B5) |
| 指标别名 | Heat shock 86kDa;HSP 86;HSP86;Hsp89;HSP89A;HSP90;HSP90A;HSP90AA1;HSP90N;HSPC1;HSPCA;HSPCAL1;HSPCAL4;HSPN;LAP2 |
| 克隆性 | Monoclonal |
| 检验物种 | human,monkey,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | HSP90AA1 |
| 克隆号 | 6B5 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | E.coli-derived human PTBP2 recombinant protein (Position:M1-A504).A synthetic peptide corresponding to a sequence at the C-terminus of human Hsp90 alpha (454-488aa QNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQ),identical to the related mouse and rat sequences. |
| 实际分子量 | 85～100KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Heat shock protein HSP 90-alpha is a protein that in humans is encoded by the HSP90AA1 gene.The gene,HSP90AA1,encodes the human stress-inducible 90-kDa heat shock protein alpha (Hsp90A).Complemented by the constitutively expressed paralog Hsp90B which shares over 85% amino acid sequence identity,Hsp90A expression is initiated when a cell experiences proteotoxic stress.Once expressed Hsp90A dimers operate as molecular chaperones that bind and fold other proteins into their functional 3-dimensional structures.This molecular chaperoning ability of Hsp90A is driven by a cycle of structural rearrangements fueled by ATP hydrolysis.Current research on Hsp90A focuses in its role as a drug target due to its interaction with a large number of tumor promoting proteins and its role in cellular stress adaptation. |
| Uniprot ID | P07900 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | heat shock protein 90kDa alpha (cytosolic),class A member 1 |
| 蛋白名全称 | Heat shock protein HSP 90-alpha |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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