产品货号：
Z38735
中文名称：
TYRO3抗体
英文名称：
Anti-TYRO3 Antibody (Clone#1444CT895.86.31)
产品规格：
80μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TYRO3 Antibody (Clone#1444CT895.86.31) |
| 指标别名 | Brt;BYK;Dtk;FLJ16467;RSE;Sky;Tif;TYRO3;TYRO3 protein tyrosine kinase;Tyrosine protein kinase byk;Tyrosine protein kinase DTK;Tyrosine protein kinase RSE;Tyrosine protein kinase SKY |
| 克隆性 | Monoclonal |
| 检验物种 | mouse |
| 应用范围 | WB |
| 基因名称 | Tyro3 |
| 克隆号 | 1444CT895.86.31 |
| 抗体来源 | Mouse |
| 免疫原 | This Tyro3 antibody is generated from a mouse immunized with a recombinant protein. |
| 计算分子量 | 96kDa |
| 成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6.Regulates many physiological processes including cell survival,migration and differentiation.Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules.Following activation by ligand,interacts with PIK3R1 and thereby enhances PI3-kinase activity.Activates the AKT survival pathway,including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes.TYRO3 signaling plays a role in various processes such as neuron protection from excitotoxic injury,platelet aggregation and cytoskeleton reorganization.Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1,which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3. |
| Uniprot ID | P55144 |
相关搜索：TYRO3抗体，TYRO3单抗，Anti-TYRO3 Antibody (Clone#1444CT895.86.31)