产品货号:
Z38718
中文名称:
Hu C5AR1抗体
英文名称:
Anti-Hu C5AR1 Antibody (Clone#S5/1)
产品规格:
0.1mg(C100)
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Hu C5AR1 Antibody (Clone#S5/1) |
指标别名 | C5A;C5a R;C5aR;C5AR1;C5R1;CD88 |
克隆性 | Monoclonal |
检验物种 | rabbit,ferret,cow,human |
应用范围 | FCM,IP,WB,IHC |
基因名称 | C5AR1 |
克隆号 | S5/1 |
抗体来源 | Mouse |
免疫原 | Recombinant N-terminal peptide (Asp15-Asp27) of human C5aR.The mouse monoclonal antibody S5/1 recognizes an extracellular epitope of CD88 protein,a 43kDa receptor of C5a component of the complement cascade. |
计算分子量 | 39kDa |
成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
纯化方式 | Purified by protein-A affinity chromatography. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | Store at 2~8℃.Do not freeze. |
背景资料 | CD88/C5aR is a G protein-coupled seven membrane-spanning protein serving as a receptor for C5a component of the complement cascade,and is expressed mainly by monocytes,macrophages,neutrophils,eosinophils,and mast cells,but also e.g.by hepatocytes,glial cells,vascular endothelial cells,or cardiomyocytes.The binding of C5a to CD88 is associated with inflammatory response,including superoxide anion production,chemotaxis,and increased production of acute phase proteins.Expression of CD88 on synovial mast cells and their C5a-mediated degranulation plays a role in pathogenesis of rheumatoid arthritis. |
Uniprot ID | P21730 |
基因名全称 | Complement C5a receptor 1 |
蛋白名全称 | C5a anaphylatoxin chemotactic receptor 1 |
推荐稀释比 | Flow cytometry:3~12μg/mL. |
相关搜索:Hu C5AR1抗体,Hu C5AR1单抗,Anti-Hu C5AR1 Antibody (Clone#S5/1)