产品货号:
Z38678
中文名称:
GDF8/Myostatin/MSTN抗体
英文名称:
Anti-GDF8/Myostatin/MSTN Antibody (Clone#6H12)
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-GDF8/Myostatin/MSTN Antibody (Clone#6H12) |
指标别名 | GDF 8;GDF8;MSTN;myostatin |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,ELISA |
基因名称 | MSTN |
克隆号 | 6H12 |
抗体来源 | Mouse |
抗体类型 | IgG |
免疫原 | Purified recombinant fragment of GDF-8 expressed in E.Coli. |
计算分子量 | 43KD |
成分 | Ascitic fluid containing 0.03% sodium azide,0.5% BSA,50% glycerol. |
纯化方式 | Affinity purification |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Myostatin (also known as growth differentiation factor 8,abbreviated GDF-8) is a myokine,a protein produced and released by myocytes that acts on muscle cells' autocrine function to inhibit myogenesis:muscle cell growth and differentiation.In humans it is encoded by the MSTN gene.This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins.Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression.The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer.This protein negatively regulates skeletal muscle cell proliferation and differentiation.Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. |
Uniprot ID | O14793 |
基因名全称 | Growth/differentiation factor 8 |
蛋白名全称 | Growth/differentiation factor 8 |
推荐稀释比 | WB 1:500~1:2000 ELISA 1:10000 |
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