产品货号：
Z38521
中文名称：
TGFBR2抗体
英文名称：
Anti-TGFBR2 Antibody (Clone#2F11)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TGFBR2 Antibody (Clone#2F11) |
| 指标别名 | AAT3;FAA3;LDS1B;LDS2B;MFS2;RIIC;TAAD2;TbetaR II;TGF beta receptor type 2;TGF beta receptor type II;TGF beta type II receptor;TGFbeta RII;TGFBR2;TGFR 2 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | TGFBR2 |
| 克隆号 | 2F11 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human TGFBR2 (96-128aa TLETVCHDPKLPYHDFILEDAASPKCIMKEKKK),different from the related mouse sequence by five amino acids,and from the related rat sequence by eight amino acids. |
| 实际分子量 | 70～85KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | TGFBR2 (transforming growth factor,beta receptor II (70/80kDa)),also known as TGF-beta receptor type-2,TGFR-2,TGF-beta type II receptor,Transforming growth factor-beta receptor type II(TGF-beta receptor type II,TbetaR-II),is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily.A TGFBR2 cDNA encodes a deduced 565-amino acid protein with a calculated molecular mass of approximately 60kD in length.The encoded protein is a transmembrane protein that has a protein kinase domain,forms a heterodimeric complex with another receptor protein,and binds TGF-beta.This receptor/ligand complex phosphorylates proteins,which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.Mutations in this gene have been associated with Marfan syndrome,Loeys-Deitz aortic aneurysm syndrome,Osler-Weber-Rendu syndrome,and the development of various types of tumors.Alternatively spliced transcript variants encoding different informs have been characterized. |
| Uniprot ID | P37173 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | transforming growth factor,beta receptor II (70/80kDa) |
| 蛋白名全称 | TGF-beta receptor type-2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：TGFBR2抗体，TGFBR2单抗，Anti-TGFBR2 Antibody (Clone#2F11)