产品货号：
Z38355
中文名称：
TRPC6抗体
英文名称：
Anti-TRPC6 Antibody (Clone#3F2.H10.F2)
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TRPC6 Antibody (Clone#3F2.H10.F2) |
| 指标别名 | FSGS2;Transient receptor protein 6;TRP 6;TRP6;TRPC6 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,IHC,WB |
| 基因名称 | TRPC6 |
| 克隆号 | 3F2.H10.F2 |
| 抗体来源 | Mouse |
| 免疫原 | This monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to a region near the carboxy terminus of human TRPC6 protein. |
| 计算分子量 | 106kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This product was purified from concentrated tissue culture supernate by Protein A chromatography.This antibody is specific for human TRPC6 protein.A BLAST analysis was used to suggest cross-reactivity with TRPC6 from chimpanzee based on 100% homology with the immunizing sequence.Cross-reactivity with TRPC6 from other sources has not been determined. |
| 浓度 | 1.0mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | TRPC6,also known as TRP6,short transient receptor potential channel 6 and transient receptor potential cation channel subfamily C member 6,is thought to form a receptor-activated non-selective calcium permeant cation channel.TRPC6 is probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors.It is activated by diacylglycerol (DAG) in a membrane-delimited fashion,independently of protein kinase C and may not to be activated by intracellular calcium store depletion.Defects in this gene are a cause of focal segmental glomerulosclerosis (FSGS).Expression of this protein has been reported in tissues such as placenta,lung,spleen,ovary,small intestine,and renal podocytes.Immunohistochemistry studies using polyclonal antibodies to this target have shown moderate to strong staining in cell types such as neurons,breast,respiratory,squamous and prostate epithelium,epidermis,placental trophoblasts,dendritic cells,and subsets of immune cells,and faint to moderate staining of adrenal,colon,ganglion cells,hepatocytes,heart,and testis. |
| Uniprot ID | Q9Y210 |
| 基因名全称 | Short transient receptor potential channel 6 |
| 推荐稀释比 | ELISA:1:10,000 - 1:50,000 IHC:2.5μg/mL WB:1:500- 1:2,000 |
相关搜索：TRPC6抗体，TRPC6单抗，Anti-TRPC6 Antibody (Clone#3F2.H10.F2)