产品货号：
Z38337
中文名称：
HNF4A抗体
英文名称：
Anti-HNF4A Antibody (Clone#6C8E9)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HNF4A Antibody (Clone#6C8E9) |
| 指标别名 | hepatocyte nuclear factor 4 alpha;FRTS4;HNF4;HNF4a7;HNF4a8;HNF4a9;HNF4alpha;MODY;MODY1;NR2A1;NR2A21;TCF;TCF14;HNF4A |
| 克隆性 | Monoclonal |
| 检验物种 | human,rat |
| 应用范围 | WB,IHC |
| 基因名称 | HNF4A |
| 克隆号 | 6C8E9 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2a |
| 免疫原 | E.coli-derived human HNF-4-alpha recombinant protein (Position:Q164-I474).Human HNF-4-alpha shares 95% and 96% amino acid (aa) sequence identity with mouse and rat HNF-4-alpha,respectively. |
| 实际分子量 | 53KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Hepatocyte nuclear factor 4 alpha (HNF4A),also known as NR2A1,is a nuclear receptor that in humans is encoded by the HNF4A gene.It is mapped to 20q13.12.HNF4A is a nuclear transcription factor that binds DNA as a homodimer.The encoded protein controls the expression of several genes,including hepatocyte nuclear factor 1 alpha,a transcription factor which regulates the expression of several hepatic genes.This gene plays a role in development of the liver,kidney,and intestines.HNF4A is required for the PXR and CAR-mediated transcriptional activation of CYP3A4.This gene also plays a pivotal role in the expression and synthesis of SHBG,an important glycoprotein made primarily in the liver,which in addition to lowering insulin-resistance also serves in reducing levels of free Oestrogen as-well as prolonging the half-life of Testosterone. |
| Uniprot ID | P41235 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P). |
| 基因名全称 | hepatocyte nuclear factor 4,alpha |
| 蛋白名全称 | Hepatocyte nuclear factor 4-alpha |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：HNF4A抗体，HNF4A单抗，Anti-HNF4A Antibody (Clone#6C8E9)