产品货号：
Z38333
中文名称：
HNF4A抗体
英文名称：
Anti-HNF4A Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HNF4A Antibody |
| 指标别名 | hepatocyte nuclear factor 4 alpha;FRTS4;HNF4;HNF4a7;HNF4a8;HNF4a9;HNF4alpha;MODY;MODY1;NR2A1;NR2A21;TCF;TCF14;HNF4A |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | HNF4A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human HNF-4-alpha |
| 实际分子量 | 53KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Hepatocyte nuclear factor 4 alpha (HNF4A),also known as NR2A1,is a nuclear receptor that in humans is encoded by the HNF4A gene.It is mapped to 20q13.12.HNF4A is a nuclear transcription factor that binds DNA as a homodimer.The encoded protein controls the expression of several genes,including hepatocyte nuclear factor 1 alpha,a transcription factor which regulates the expression of several hepatic genes.This gene plays a role in development of the liver,kidney,and intestines.HNF4A is required for the PXR and CAR-mediated transcriptional activation of CYP3A4.This gene also plays a pivotal role in the expression and synthesis of SHBG,an important glycoprotein made primarily in the liver,which in addition to lowering insulin-resistance also serves in reducing levels of free Oestrogen as-well as prolonging the half-life of Testosterone. |
| Uniprot ID | P41235 |
| 基因名全称 | Hepatocyte nuclear factor 4-alpha |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100ICC/IF 1:50～1:200 FC 1:50 |
相关搜索：HNF4A抗体，HNF4A单抗，Anti-HNF4A Antibody