产品货号:
Z38141
中文名称:
ESRP1抗体
英文名称:
Anti-ESRP1 Antibody (Clone#27H12)
产品规格:
100μg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ESRP1 Antibody (Clone#27H12) |
指标别名 | ESRP1;RBM35A;RNA binding motif protein 35A;RNA binding protein 35A |
克隆性 | Monoclonal |
检验物种 | mouse |
应用范围 | WB |
基因名称 | ESRP1 |
克隆号 | 27H12 |
抗体来源 | Mouse |
抗体类型 | IgG2b |
免疫原 | Anti-Esrp-1 was produced by repeated immunizations of full length recombinant mouse Esrp-1 fusion protein. |
计算分子量 | 76kDa |
成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
纯化方式 | This product is an IgG fraction antibody purified by Protein-A chromatography followed by extensive dialysis against the buffer stated above.This antibody reacts with mouse Esrp-1 protein.A BLAST analysis of the immunizing protein sequence shows 100% homology with Esrp-1 from mouse and a 91% sequence homology with Esrp-1 from human,pig,rat,opossum,horse,cattle,panda,dog,and chimpanzee.The binding epitope of this monoclonal antibody has not been mapped. |
浓度 | 1.0mg/mL by UV absorbance at 280nm |
产品形态 | 溶液 |
保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
背景资料 | Epithelial splicing regulatory protein 1 (Esrp-1) is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms.It specifically regulates the expression of FGFR2-IIIb,an epithelial cell-specific isoform of FGFR2,and also regulates the splicing of CD44,CTNND1,ENAH,3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT).EsrpP-1 acts by directly binding specific sequences in mRNAs.It binds the GU-rich sequence motifs in the ISE/ISS-3,a cis-element regulatory region present in the mRNA of FGFR2. |
Uniprot ID | Q3US41 |
基因名全称 | Epithelial splicing regulatory protein 1 |
推荐稀释比 | ELISA:1:750,000 WB:1:1000 |
相关搜索:ESRP1抗体,ESRP1单抗,Anti-ESRP1 Antibody (Clone#27H12)