产品货号：
Z38062
中文名称：
FER抗体
英文名称：
Anti-FER Antibody (Clone#1487CT794.8.50)
产品规格：
80μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FER Antibody (Clone#1487CT794.8.50) |
| 指标别名 | FER;p94 Fer;Proto oncogene c Fer;TYK3;Tyrosine kinase 3;Tyrosine protein kinase Fer |
| 克隆性 | Monoclonal |
| 检验物种 | mouse |
| 应用范围 | WB,FCM,IF |
| 基因名称 | Fer |
| 克隆号 | 1487CT794.8.50 |
| 抗体来源 | Mouse |
| 免疫原 | This Fer antibody is generated from a mouse immunized with a recombinant protein. |
| 计算分子量 | 95kDa |
| 成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton,microtubule assembly,lamellipodia formation,cell adhesion,cell migration and chemotaxis.Acts downstream of EGFR,KIT,PDGFRA and PDGFRB.Acts downstream of EGFR to promote activation of NF-kappa-B and cell proliferation.May play a role in the regulation of the mitotic cell cycle.Plays a role in the insulin receptor signaling pathway and in activation of phosphatidylinositol 3-kinase.Acts downstream of the activated FCER1 receptor and plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells.Plays a role in the regulation of mast cell degranulation.Plays a role in leukocyte recruitment and diapedesis in response to bacterial lipopolysaccharide (LPS).Phosphorylates CTTN,CTNND1,PTK2/FAK1,GAB1,PECAM1 and PTPN11.May phosphorylate JUP and PTPN1.Can phosphorylate STAT3 according to PubMed:10878010 and PubMed:19159681,but clearly plays a redundant role in STAT3 phosphorylation.According to PubMed:11134346,cells where wild type FER has been replaced by a kinase-dead mutant show no reduction in STAT3 phosphorylation.Phosphorylates TMF1.Isoform 3 lacks kinase activity. |
| Uniprot ID | P70451 |
相关搜索：FER抗体，FER单抗，Anti-FER Antibody (Clone#1487CT794.8.50)