产品货号:
Z38045
中文名称:
FH抗体
英文名称:
Anti-FH Antibody (Clone#9D8)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-FH Antibody (Clone#9D8) |
指标别名 | FH;Fumarase;fumarate hydratase;HLRCC;LRCC;MCL;MCUL1 |
克隆性 | Monoclonal |
检验物种 | human,monkey,mouse,rat |
应用范围 | WB,IHC,ICC/IF |
基因名称 | FH |
克隆号 | 9D8 |
抗体来源 | Mouse |
抗体类型 | IgG2a |
免疫原 | A synthetic peptide corresponding to a sequence of human FH (YDKAAKIAKTAH KNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK). |
实际分子量 | 50KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | protein G purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Fumarase (or fumaratehydratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate.Fumarase comes in two forms:mitochondrial and cytosolic.The mitochondrial isoenzyme is involved in the Krebs Cycle (also known as the Tricarboxylic Acid Cycle [TCA] or the Citric Acid Cycle),and the cytosolic isoenzyme is involved in the metabolism of amino acids and fumarate.Subcellular localization is established by the presence of a signal sequence on the amino terminus in the mitochondrial form,while subcellular localization in the cytosolic form is established by the absence of the signal sequence found in the mitochondrial variety.This enzyme participates in 2 metabolic pathways:citric acid cycle,reductive citric acid cycle (CO2 fixation),and is also important in renal cell carcinoma.Mutations in this gene have been associated with the development of leiomyomas in the skin and uterus in combination with renal cell carcinoma. |
Uniprot ID | P07954 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:50~400 Immunohistochemistry in paraffin section (IHC) 1:50~400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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