产品货号：
Z38040
中文名称：
FHIT抗体
英文名称：
Anti-FHIT Antibody (Clone#26H7)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FHIT Antibody (Clone#26H7) |
| 指标别名 | Fragile histidine triad diadenosine triphosphatase;AP3Aase;FRA3B;FHIT |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,ICC/IF,FCM |
| 基因名称 | FHIT |
| 克隆号 | 26H7 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | E.coli-derived human FHIT recombinant protein (Position:M1-Q147).Human FHIT shares 90% and 87% amino acid (aa) sequence identity with mouse and rat FHIT,respectively. |
| 实际分子量 | 17KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Bis(5'-adenosyl)-triphosphatase,also known as fragile histidine triad protein (FHIT) is an enzyme that in humans is encoded by the FHIT gene.This gene,a member of the histidine triad gene family,encodes a diadenosine P1,P3-bis(5'-adenosyl)-triphosphate adenylohydrolase involved in purine metabolism.The gene encompasses the common fragile site FRA3B on chromosome 3p14.2,where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene.In fact,aberrant transcripts from this gene have been found in about half of all esophageal,stomach,and colon carcinomas.Furthermore,FHIT has been shown to synergize with VHL,another tumor suppressor,in protecting against chemically - induced lung cancer.It also acts as a tumor suppressor of HER2/neu driven breast cancer. |
| Uniprot ID | P49789 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells |
相关搜索：FHIT抗体，FHIT单抗，Anti-FHIT Antibody (Clone#26H7)