产品货号：
Z37974
中文名称：
FGF21抗体
英文名称：
Anti-FGF21 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FGF21 Antibody |
| 指标别名 | FGF 21;FGF21;fibroblast growth factor 21 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | FGF21 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human FGF21 |
| 实际分子量 | 22KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | FGF21 (Fibroblast growth factor 21) is a protein that in humans is encoded by the FGF21 gene,which is also a member of the fibroblast growth factor (FGF) family.The FGF21 gene is mapped on 19q13.33.Using RT-PCR,Fgf21 was expressed in several types of adipose tissue in mice,including subcutaneous and epididymal fat pads and brown adipose tissue.The level of Fgf21 expression in adipose tissue was comparable to that in liver.FGF21 stimulates glucose uptake in adipocytes but not in other cell types.This effect is additive to the activity of insulin.FGF21 treatment of adipocytes is associated with phosphorylation of FRS2,a protein linking FGF receptors to the Ras/MAP kinase pathway.FGF21 also protects animals from diet-induced obesity when overexpressed in transgenic mice and lowers blood glucose and triglyceride levels when administered to diabetic rodents.Changes in Fgf21 expression due to suckling or nutritional manipulations were associated with changes in circulating free fatty acid and ketone body levels.In differentiated mouse brown adipocytes in culture,Fgf21 treatment increased the expression of thermogenic genes,caused higher total and uncoupled respiration,and enhanced glucose oxidation. |
| Uniprot ID | Q9NSA1 |
| 基因名全称 | Fibroblast growth factor 21 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 |
相关搜索：FGF21抗体，FGF21单抗，Anti-FGF21 Antibody