产品货号：
Z37850
中文名称：
Glucocorticoid receptor/NR3C1抗体
英文名称：
Anti-Glucocorticoid receptor/NR3C1 Antibody (Clone#OTI2C4)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Glucocorticoid receptor/NR3C1 Antibody (Clone#OTI2C4) |
| 指标别名 | GCCR;GCR;Glucocorticoid receptor;GR;GRL;NR3C1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | NR3C1 |
| 克隆号 | OTI2C4 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | Human recombinant protein fragment corresponding to amino acids 1-265 of human NR3C1(NP_000167) produced in E.coli. |
| 实际分子量 | 85.5KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | This gene encodes glucocorticoid receptor,which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription,and as a regulator of other transcription factors.This receptor is typically found in the cytoplasm,but upon ligand binding,is transported into the nucleus.It is involved in inflammatory responses,cellular proliferation,and differentiation in target tissues.Mutations in this gene are associated with generalized glucocorticoid resistance.Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms.Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described,and shown to be functional,displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175).[provided by RefSeq,Feb 2011] |
| Uniprot ID | P06536 |
| 推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:150 |
相关搜索：Glucocorticoid receptor/NR3C1抗体，Glucocorticoid receptor抗体，NR3C1单抗