产品货号：
Z37840
中文名称：
GLUT1/SLC2A1抗体
英文名称：
Anti-GLUT1/SLC2A1 Antibody (Clone#10C10)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GLUT1/SLC2A1 Antibody (Clone#10C10) |
| 指标别名 | DYT17;DYT18;GLUT;GLUT 1;GLUT1;HepG2 glucose transporter;PED;SLC2A1 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | SLC2A1 |
| 克隆号 | 10C10 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | E.coli-derived human SLC2A1 recombinant protein (Position:R92-V492).Human SLC2A1 shares 98% and 98.3% amino acid (aa) sequence identity with mouse and rat SLC2A1,respectively. |
| 实际分子量 | 55KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | GLUT1,also known as SLC2A1,is a major glucose transporter in the mammalian blood-brain barrier whose gene is mapped to 1p35-p31.3 and contains 10 exons.It is present at high levels in primate erythrocytes and brain endothelial cells.Not only can transport dehydroascorbic acid (the oxidized form of vitamin C) into the brain,GLUT1 is also likely to contribute to HTLV-associated disorders through interacting with HTLV envelope glycoproteins.Functionally,GLUT1 deficiency causes a decrease in embryonic glucose uptake and apoptosis,which may be involved in diabetic embryopathy,by contrast,an increased expression of GLUT1 in some malignant tumors may suggest a role for glucose-derivative tracers to detect in vivo thyroid cancer metastases by positron-emission tomography scanning. |
| Uniprot ID | P11166 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry(Paraffin-embedded Section) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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