产品货号：
Z37818
中文名称：
FYN Purified抗体
英文名称：
Anti-FYN Purified Antibody (Clone#FYN-01)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FYN Purified Antibody (Clone#FYN-01) |
| 指标别名 | FYN;p59 Fyn;Proto oncogene c Fyn;Proto oncogene Syn;SLK;Src like kinase;SYN;Tyrosine protein kinase Fyn |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse |
| 应用范围 | IP,WB,IHC,ICC |
| 基因名称 | FYN |
| 克隆号 | FYN-01 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | Bacterially expressed recombinant fragment of human Fyn (aa 7-176).The mouse monoclonal antibody FYN-01 recognizes Fyn,a 59kDa non-receptor Src-family protein tyrosine kinase (intracellular antigen). |
| 计算分子量 | 61kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | Fyn is a ubiquitously expressed Src-family protein tyrosine kinase with important roles e.g.in immune and nervous system.It regulates N-methyl-D-aspartate (NMDA) receptor functions,thus affecting various brain functions,and even many of its other substrates are important for neural migration,synaptic plasticity,oligodendrocyte differentiation,and axon growth and guidance.In immune system Fyn namely regulates the commitment of T cells to activation,is important in T cell anergy induction,promotes mast cell chemotaxis and reorganization of cytoskeleton and participates in mast cell activation.Fyn is also involved in embryonic stem cell growth and differentiation,associates with tubulin and may play roles in mitotic spindle formation. |
| Uniprot ID | P06241 |
| 基因名全称 | FYN proto-oncogene,Src family tyrosine kinase |
| 蛋白名全称 | Tyrosine-protein kinase Fyn |
| 推荐稀释比 | Immunohistochemistry (paraffin sections):5μg/mL;positive tissue:brain. Western blotting:2μg/mL;positive control:JURKAT human T cell leukemia cell line. Immunoprecipitation:positive control:J77 T cell line.Preparation of cell lysate:30min on ice (orbital incubator) in lysing buffer,lysing buffer with N-dodecyl beta-D-maltoside (20mM Tris/Cl,100mM NaCl pH8,2,1% laurylmaltosid (w/v),50mM NaF).The antibody FYN-01 apparently gives very specific signal (by 59kDa),and nicely immunoprecipitates Fyn from cell lysates. |
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