产品货号：
Z37807
中文名称：
HSD17B2抗体
英文名称：
Anti-HSD17B2 Antibody (Clone#OTI4F10)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HSD17B2 Antibody (Clone#OTI4F10) |
| 指标别名 | 17 beta HSD 2;17βHSD2;20 alpha HSD;E2DH;EDH17B2;HSD17;HSD17B2;SDR9C2 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,FCM |
| 基因名称 | HSD17B2 |
| 克隆号 | OTI4F10 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Full length human recombinant protein of human HSD17B2(NP_002144) produced in HEK293T cell. |
| 实际分子量 | 42.6KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 0.45mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | HSD17B2(17-BETA-HYDROXYSTEROID DEHYDROGENASE II),also called 17-BETA-HSD II,is an anzyme which have 387 amino acids with a predicted molecular weight of 42,782 and associate with the membranes of the endoplasmic reticulum.Its Cytogenetic location is 16q23.3.The type 2 enzyme was capable of catalyzing the interconversion of testosterone and androstenedione,as well as estradiol and estrone.HSD17B2 mRNA was detected in 18 of 42(43%) adenomas but not in prolactinomas.In the human endometrium,inactivation of 17-beta-estradiol to estrone is catalyzed by HSD17B2.And HSD17B2 activity distinguishing between disease-free and diseased endometria.HSD17B2 efficiently catalyzes the oxidative metabolism of androgens and estrogens,and it is expressed in a large series of human peripheral tissues.The previous paradigm that HSD17B2 activity in the endometrium is elevated during the secretory phase is confined to diseased endometrium but not to disease-free endometrium. |
| Uniprot ID | P37059 |
| 基因名全称 | hydroxysteroid (17-beta) dehydrogenase 2 |
| 蛋白名全称 | Estradiol 17-beta-dehydrogenase 2 |
| 推荐稀释比 | Western blot (WB) 1:2000 Flow cytometry (FCM) 1:100 |
相关搜索：HSD17B2抗体，HSD17B2单抗，Anti-HSD17B2 Antibody (Clone#OTI4F10)