产品货号：
Z37769
中文名称：
Hu CD53 Purified抗体
英文名称：
Anti-Hu CD53 Purified Antibody (Clone#MEM-53)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Hu CD53 Purified Antibody (Clone#MEM-53) |
| 指标别名 | CD53 molecule;MOX44;TSPAN25 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | FCM,IP,WB,IHC-F |
| 基因名称 | CD53 |
| 克隆号 | MEM-53 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Leukocytes of pacient suffering from a LGL-type leukemia.The antibody MEM-53 reacts with an extracellular epitope of CD53,a 32～40kDa tetraspanin family glycoprotein exclusivelly expressed on leukocytes;it is not present on platelets,red blood cells and non-hematopoietic cells.The antibody MEM-53 reacts also with deglycosylated molecule (molecular weight of the antigen is reduced by 15kDa using endoglycosidase F). |
| 计算分子量 | 24kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage.This molecule has been reported to form complexes with other leukocyte surface proteins such as CD2,CD19,CD21,MHC II,VLA-4 or tetraspanins CD37,CD81 and CD82,thus probably modulating various signaling processes.CD53 is involved in radioresistancy of tumour cells and its triggering has anti-apoptotic effect.In thymus,CD53 is up-regulated in response to positive selection signals during T cell development,and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide,whereas stimulation of neutrophils results in down-regulation of CD53 expression. |
| Uniprot ID | P19397 |
| 基因名全称 | CD53 molecule |
| 蛋白名全称 | Leukocyte surface antigen CD53 |
| 推荐稀释比 | Immunohistochemistry (frozen sections):It is suitable for discrimination of lymphomas from other tumors. Flow cytometry:4μg/mL. |
相关搜索：Hu CD53 Purified抗体，Hu CD53 Purified单抗，Anti-Hu CD53 Purified Antibody (Clone#MEM-53)