产品货号：
Z37762
中文名称：
Hu CD42b/GP1BA Purified抗体
英文名称：
Anti-Hu CD42b/GP1BA Purified Antibody (Clone#HIP1)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Hu CD42b/GP1BA Purified Antibody (Clone#HIP1) |
| 指标别名 | BSS;CD42b;CD42b alpha;GP1B;GP1BA |
| 克隆性 | Monoclonal |
| 检验物种 | primate,human |
| 应用范围 | FCM,IHC-F |
| 基因名称 | GP1BA |
| 克隆号 | HIP1 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Peripheral blood mononuclear cells of a patient suffering with CLL.The antibody HIP1 reacts with an extracellular epitope of CD42b (GPIb alpha),a 135～145kDa membrane glycoprotein expressed on platelets and megakaryocytes.CD42b and CD42c (GPIb beta) are composed in a disulfide linked heterodimer (CD42b/c;160kDa);CD42b/c forms a noncovalent complex with CD42a and CD42d. |
| 计算分子量 | 72kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | CD42b (GPIb alpha) composes together with GPIb beta,GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface.CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury,as well as to thrombin,coagulation factors XI and XII,high molecular weight kininogen,TSP-1,integrin Mac-1 and P-selectin.The extracellular domain of CD42b by its interactions also contributes to metastasis. |
| Uniprot ID | P07359 |
| 基因名全称 | Glycoprotein Ib platelet subunit alpha |
| 蛋白名全称 | Platelet glycoprotein Ib alpha chain |
| 推荐稀释比 | Flow cytometry:1～4μg/mL |
相关搜索：Hu CD42b/GP1BA Purified抗体，Hu CD42b抗体，GP1BA Purified单抗