产品货号：
Z37623
中文名称：
Fibrinogen Beta Chain/FGB抗体
英文名称：
Anti-Fibrinogen Beta Chain/FGB Antibody (Clone#6D12)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Fibrinogen Beta Chain/FGB Antibody (Clone#6D12) |
| 指标别名 | FGB;fibrinogen beta chain |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | FGB |
| 克隆号 | 6D12 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human FGB (193-225aa TNLRVLRSILENLRSKIQKLESDVSAQMEYCRT),different from the related mouse sequence by three amino acids,and from the related rat sequence by five amino acids. |
| 实际分子量 | 56KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Fibrinogen beta chain,mapped to 4q31.3,is also known as?FGB.The protein encoded by this gene is the beta component of fibrinogen,a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains.Following vascular injury,fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots.In addition,various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading,display vasoconstrictor and chemotactic activities,and are mitogens for several cell types.Mutations in this gene lead to several disorders,including afibrinogenemia,dysfibrinogenemia,hypodysfibrinogenemia and thrombotic tendency.Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | P02675 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | fibrinogen beta chain |
| 蛋白名全称 | Fibrinogen beta chain |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section IHC 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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